de novo design

The Jungle of Generative Drug Discovery: Traps, Treasures, and Ways Out

Surprising pitfalls in common evaluation approaches for molecule libraries generated by deep learning models. Simple solutions are proposed.

A Hitchhiker's Guide to Deep Chemical Language Processing for Bioactivity Prediction

Practical guidelines for training deep learning models on molecular string representations for bioactivity prediction.

Chemical Language Modeling with Structured State Space Sequence Models

A novel approach to chemical language modeling. First application of structured state space sequence models (S4) to *de novo* design.